Sesquiterpene lactones from Cichorium endivia L. and C. intybus L. and cytotoxic activity.

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Sesquiterpene lactones in a hairy root culture of Cichorium intybus.

A transformed root culture of Cichorium intybus L. (Asteraceae) was found to produce sesquiterpene lactones of guaiane and germacrane type. Lactucopicrin, 8-desoxylactucin and three sesquiterpene lactone glycosides: crepidiaside B, sonchuside A and ixerisoside D were isolated from the roots. The yield of 8-desoxylactucin reached 0.03 g l(-1) at the early stationary phase of the culture.

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1988

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.36.2423